Streptomyces venezuelae metabolite implicated in Parkinson's disease-like neuron destruction
A microbial metabolite -- the product of a known human microbiome bacteria Streptomyces venezuela -- was discovered to have a destructive effect that led to neurodegeneration similar to Parkinson's disease. The study further verified the metabolite's Parkinson's disease-like effect on nematodes. The metabolite affected the movement patterns of the nematodes.
The study points to the need to research the condition of the human microbiome in causing Parkinson's disease or possibly even other diseases.
Incidentally, the genus Streptomyces is a unique subgroup of actinomycetes bacteria that are prolific producers of antibiotics
Microbial metabolites as risk factors for Parkinson's disease -- Medical Xpress
Parkinson’s Disease: Causes, Symptoms, and Treatments | National Institute on Aging
Defining the Human Microbiome - PMC
Streptomyces venezuelae - Search Results - PubMed
Streptomyces venezuelae - Wikipedia
Parkinson's disease - Wikipedia
Streptomyces venezuelae as an antiobiotic producer - Google Search