Streptomyces venezuelae metabolite implicated in Parkinson's disease-like neuron destruction

A microbial metabolite -- the product of a known human microbiome bacteria Streptomyces venezuela -- was discovered to have a destructive effect that led to neurodegeneration similar to Parkinson's disease. The study further verified the metabolite's Parkinson's disease-like effect on nematodes. The metabolite affected the movement patterns of the nematodes.

The study points to the need to research the condition of the human microbiome in causing Parkinson's disease or possibly even other diseases.

Incidentally, the genus Streptomyces is a unique subgroup of actinomycetes bacteria that are prolific producers of antibiotics

Microbial metabolites as risk factors for Parkinson's disease -- Medical Xpress

Parkinson’s Disease: Causes, Symptoms, and Treatments | National Institute on Aging

Defining the Human Microbiome - PMC

Streptomyces venezuelae - Search Results - PubMed

Streptomyces venezuelae - Wikipedia

Human microbiome - Wikipedia

Parkinson's disease - Wikipedia

Streptomyces venezuelae as an antiobiotic producer - Google Search